We periodically acknowledge advances and discoveries made with mass spectrometry and liquid chromatography. We know that often good work builds on previous foundations, which is why we provide a strong foundation for all mass specs with our dedicated lab furniture. In this post, we look at three innovations making a difference around the world.
Mass Spectrometry Aids in Determining Olive and Olive-Oil Safety
One ongoing issue with mass spectrometry is the harmful presence of lipids in samples that complicates the analysis of fatty foods. Researchers in Spain developed a novel analytical process that uses aminopropyl as a sorbent material and a Florisil cleanup in the elution step. These researchers used mass spectrometry twice—first GC-MS in SIM mode and then LC-MS-MS in positive ionization mode—to collect usable recoveries, which efficiently tested pesticide and herbicide levels in olives and olive oil. The development of this key process met newer, more stringent regulations regarding maximum contaminant levels set for olives and olive oil by the European Union and the United Nation’s Codex Alimentarius Commission of the Food and Agriculture Organization.
Quantifying Polycyclic Aromatic Hydrocarbons
Another methodology developed in the European Union determined and quantified nineteen polycyclic aromatic hydrocarbons (PAHs). Exposure to PAHs has been linked to multiple types of cancer; the EU prioritized fifteen of those nineteen PAHs for monitoring. A group of French researchers met the challenge and developed a process to determine PAHs in food and oil samples. The selective extraction of GC and tandem mass spectrometry, along with an isotope-dilution approach using 13C-labelled PAHs, provided greatly purified analytes. The methodology was quick and automated and provided high levels of sensitivity, selectivity, and interpretation.
Recording and Evaluating Mass Spectra in Their Native Environment
The ability to record mass spectra in ordinary samples in their native environment has been a holy grail for mass spectrometry. Researchers at Purdue University stepped toward this goal by developing ambient mass spectrometry. Using desorption electrospray ionization, they directed electrically charged droplets at the object of interest and then vacuumed up the released ions into the MS; rapid analysis took place on-site. Multiple uses for portable mass specs include explosives detection, natural-products discovery, and biological-tissue imaging.
Each of these examples demonstrate how researchers continue innovating applications of mass spectrometry that address real-world challenges. We celebrate these achievements and look forward to learning about more ways that mass spectrometry makes a difference.
Our IonBench dedicated lab furniture can be customized for each make and model of mass spec and HPLC so that researchers can focus on science and not on the inadequate support of their lab tables. To learn more about how our lab benches can be a firm foundation for your innovative work, contact Tim Hawkins via email or at 1-888-669-1233.