As an LC/MS researcher, you know that diffusion, void volume and the resultant peak tailing are some issues that can cause your test results to fall short of perfection. You don’t want to undo the good work of your liquid or gas chromatography by having a long transfer line between your HPLC and your mass spec. We’ve designed the IonBench dedicated lab furniture to assist your CE or LC in getting “up close and personal” for mass spectrometry that’s as close to performance perfection as possible.
Raising Your Mass Spectrometry Results to New Heights
The classic configuration between LCs and mass spectrometers involves placing them on a single piece of dedicated lab furniture. Then a transfer line that can be as long as three feet is stretched from the column effluent of the LC or GC to the inlet on the mass spec. During those three feet, the column separation begins to diffuse, and nobody wants that.
This is why we designed our HPLC-UHPLC lab bench with adjustable height ranges. You can place your LC on this separate bench and move the LC up or down in order to make the column effluent and source as close together as possible. The adjustable heights of our standard benches range from 45 cm or 17.7 inches all the way up to 97 cm or 37.7 inches. We can also craft custom dedicated lab furniture configurations upon request, if these heights will not work for your perfect scenario.
Our HPLC-UHPLC Lab Bench Gets Around
We also put our HPLC-UHPLC bench on caster wheels to make it easy to maneuver. This means that, in addition to raising your LC to the perfect height, you can also move it closer to your mass spec, further minimizing the diffusion that comes from void volume in your transfer line. In fact, test results have proven that you can optimize the performance of your LC/MS combination by adjusting position X, Y and height H, so that the column is as close as possible to the mass spectrometry source. With this optimization, we have seen void volume decrease from 50 µL to just 10 µL, for a 25% improvement in throughput and an astounding 50% improvement in resolution.
There are other reasons why putting our lab bench on casters will make sense in your lab. Perhaps you need to run the same sample on a Triple Quad and on a TOF or Orbitrap to get a more qualitative result. Rather than restarting the entire process on another LC, you can simply slide the first LC over to the other mass spec, hook it up, and be injecting in just ten minutes.
Additional Reasons for Investing in Dedicated Lab Furniture
Beyond improved performance, safety is another reason for investing in our lab benches. When it’s time to service your LC, reaching the top of the chromatograph can prove difficult—and hiring former basketball players as lab techs isn’t always an option! Rather than dragging a stepstool out of a nearby storage room or standing on a desk chair (perhaps even one on wheels, yikes!) to reach the solvent reservoir, you can easily lower the HPLC-UHPLC bench and keep your feet firmly, and safely, on the floor.
The lockable caster wheels on our lab benches also make it easy to reconfigure your lab when new test sequences are needed, or additional mass spectrometry tasks performed. No backs will be strained or injured, and you won’t need to schedule downtime in the lab to move the furniture around. Simply unlock the casters and easily move your machines.
To learn more about the time and energy-saving benefits of IonBench dedicated lab furniture, contact us today.